Profhilo vs Botox vs Fillers: Which Treatment Is Right for You?
Patient Education

Profhilo vs Botox vs Fillers: Which Treatment Is Right for You?

Dr Maryna StartsevaAesthetic Doctor, SW11 Medical Clinic
20 February 20267 min read

Understanding the Three Most Popular Aesthetic Treatments

If you're considering non-surgical aesthetic treatments in Clapham, you've likely come across three names: Profhilo, Botox, and dermal fillers. While all three address signs of ageing, they work in fundamentally different ways — and choosing the right one (or combination) depends entirely on your specific concerns.

As a doctor with over 14 years of experience in aesthetic medicine, I see patients every day who are confused about which treatment they need. This guide will help you understand the differences and make an informed decision.

How Each Treatment Works

Botox (Anti-Wrinkle Injections)

What it does: Botox temporarily relaxes the muscles that cause dynamic wrinkles — the lines that appear when you frown, raise your eyebrows, or squint.

Best for:

  • Forehead lines
  • Frown lines (the "11s" between your eyebrows)
  • Crow's feet around the eyes
  • Bunny lines on the nose

How it works: Botulinum toxin type A blocks the nerve signals to specific muscles, preventing them from contracting. The overlying skin smooths out as a result.

Results: Visible within 3–7 days, full effect at 2 weeks. Lasts 3–6 months.

At SW11 Medical Clinic: From £175 per area, £320 for 3 areas.

Dermal Fillers

What they do: Fillers add volume to areas that have lost fullness due to ageing, or enhance features like lips and cheekbones.

Best for:

  • Lip augmentation
  • Cheek volume restoration
  • Nasolabial folds (smile lines)
  • Jawline definition
  • Tear trough (under-eye hollows)
  • Chin projection

How they work: Hyaluronic acid gel is injected beneath the skin to add volume, smooth wrinkles, or sculpt facial contours.

Results: Immediate, with final results at 2 weeks. Lasts 6–18 months depending on area.

At SW11 Medical Clinic: From £360 for 0.5ml. For an in-depth look at lip enhancement specifically, read our Complete Guide to Lip Fillers in Clapham, or explore all filler options in our Dermal Fillers Guide.

Profhilo

What it does: Profhilo is a bio-remodelling treatment that improves overall skin quality — hydration, firmness, and elasticity — rather than adding volume or freezing muscles.

Best for:

  • Skin laxity (loose, crepey skin)
  • Fine lines and dullness
  • Dehydrated skin
  • Overall skin rejuvenation
  • Neck, hands, and décolletage

How it works: Ultra-pure hyaluronic acid (one of the highest concentrations on the market at 64mg/2ml) is injected at 5 specific bio-aesthetic points on each side of the face. It spreads beneath the skin and stimulates 4 types of collagen and elastin production.

Results: Gradual improvement over 2–3 months. Optimal results after 2 sessions (4 weeks apart). Lasts 6–12 months.

At SW11 Medical Clinic: £350 per session, £650 for a course of 2.

Side-by-Side Comparison

FeatureBotoxDermal FillersProfhilo
Primary purposeRelax muscles / smooth wrinklesAdd volume / sculpt featuresImprove skin quality
Best age group25–65+25–65+30–65+
Treatment time10–20 minutes20–45 minutes20 minutes
Pain levelMinimal (fine needles)Mild (numbing included)Mild (5 injection points)
Results visible3–7 daysImmediate2–4 weeks
Duration3–6 months6–18 months6–12 months
DowntimeNone1–3 days mild swellingNone
Starting price£175£360£350
ReversibleWears off naturallyYes (hyaluronidase)Wears off naturally

Can You Combine Treatments?

Absolutely — and many of our patients do. In fact, combining treatments often produces the best overall results. Common combinations include:

Botox + Fillers (The Classic Combo)

Botox smooths the upper face (forehead, crow's feet) while fillers restore volume in the mid and lower face (cheeks, lips, jawline). This addresses both dynamic wrinkles and volume loss.

Profhilo + Botox (The Glow-Up)

Profhilo improves overall skin quality and hydration, while Botox targets specific wrinkles. The result is smoother, more radiant skin with fewer lines.

All Three (The Full Rejuvenation)

For patients seeking comprehensive facial rejuvenation, we often recommend all three treatments staged over several weeks. The order typically is:

1Profhilo first (to improve skin quality)
2Botox 2 weeks later (to relax dynamic wrinkles)
3Fillers 2 weeks after Botox (to add volume where needed)

Which Treatment Should You Choose?

Choose Botox if:

  • Your main concern is forehead lines, frown lines, or crow's feet
  • You want a quick treatment with zero downtime
  • You're looking for preventative treatment (popular with patients in their late 20s–30s) — read more in our guide on what age to start Botox

Choose Fillers if:

  • You want to add volume to lips, cheeks, or jawline
  • You have deep static wrinkles (nasolabial folds, marionette lines)
  • You want to sculpt or contour specific facial features

Choose Profhilo if:

  • Your skin looks tired, dull, or dehydrated
  • You're noticing skin laxity (especially on the neck or lower face)
  • You want an overall improvement in skin quality without changing your features
  • You prefer a subtle, natural approach

Book a Consultation at SW11 Medical Clinic

Still unsure which treatment is right for you? That's exactly what consultations are for. You might also find it helpful to read our guide on how to choose an aesthetic clinic in Clapham or see how we compare to other clinics in our Best Aesthetic Clinic in Clapham article. Book a free consultation at our CQC-registered clinic in Clapham, and our experienced doctors will assess your concerns and recommend the most effective treatment plan.

SW11 Medical Clinic | 4 Battersea Rise, London SW11 1ED | 020 7223 5114

Ready to Book Your Treatment?

Free consultation with our qualified doctors and nurse practitioners. CQC-registered clinic in Clapham.